Diagnostic dilemma: A woman born without a vagina or cervix conceived a son naturally.

Patient: 16-year-old girl living in the UK Symptoms: The teenage girl was referred to a pediatric and adolescent gynecology clinic in 1999, doctors wrote in a case report. She was experiencing pelvic pain following the regular pattern of her menstrual cycle, but her first period had not yet arrived. She was referred for “amenorrhea,” meaning […]

A single protein could dramatically change the trajectory of Alzheimer’s disease

We now know why a single genetic mutation can protect against Alzheimer’s disease in people destined to develop it at a very young age. The genetic mutation affects a protein called Reelin, which tells brain cells to shred toxic amyloid plaques and tau tangles that may be responsible for the disease. This mutation makes Reelin […]