The United States has launched a wide-ranging federal initiative aimed at redefining the nation’s scientific and technological future.
The new mandate, known as the Genesis Mission, is framed as one of the most ambitious U.S. research efforts in decades rooted in the accelerating power of AI computing.
The mission, announced in a White House executive order, will be led by the Department of Energy and is designed to fundamentally expand America’s scientific capabilities, increase global competitiveness, and ensure long-term technological advantage.
The administration says the initiative will effectively “double” U.S. science and engineering productivity over the next decade.
Commenting on this initiative, Energy Secretary Chris Wright said: “Throughout our history, from the Manhattan Project to the Apollo Program, our nation’s brightest minds and industries have answered the call in times of national need.
“Now America is calling on them again. The Genesis mission will unleash the full power of our national laboratories, supercomputers, and data resources to ensure America becomes the world leader in artificial intelligence and usher in a new golden age of American discovery.”
An AI computing ecosystem built for breakthroughs
The Genesis mission builds on President Trump’s previous executive orders aimed at removing regulatory hurdles to U.S. AI development and the U.S. AI Action Plan announced earlier this year.
Together, these directives form a comprehensive national blueprint to reduce dependence on foreign technology, enable advanced research, and accelerate scientific progress.
Secretary of Energy Wright appointed Undersecretary of Science Dario Gil to lead the mission.
Under his direction, the Department of Energy’s 17 national laboratories will collaborate with commercial technology leaders and major academic institutions to build an unprecedented integrated discovery platform.
The system, which officials describe as the most complex scientific instrument ever attempted, combines the nation’s top supercomputers with advanced AI computing frameworks, next-generation quantum technology and state-of-the-art research facilities.
In total, more than 40,000 federal scientists, engineers, and technical experts will contribute, along with U.S. industry partners developing technology that will shape decades of global innovation.
Targeting energy, science and security
The administration has identified three major national priorities for the Genesis Mission.
First, the initiative aims to secure U.S. energy leadership by deploying AI tools to accelerate advances in nuclear fusion, next-generation nuclear systems, and modernized power grid technologies. Officials say this could pave the way for more resilient and affordable domestically sourced energy solutions.
Second, the mission is designed to foster fundamental scientific discovery. Through major investments in quantum research and close collaboration with private industry, the United States wants to build a robust ecosystem that can generate innovative breakthroughs across physics, materials science, and biotechnology.
Finally, national security stands as a central pillar. DOE plans to expand the use of AI computing to create new AI-driven tools to ensure the safety and reliability of the U.S. nuclear stockpile, develop advanced materials for defense applications, and strengthen homeland security.
With the Genesis mission currently underway, the administration is positioning AI computing as the engine driving America’s next era of scientific and strategic leadership.
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